Single-port laparoscopically collected omental flap for immediate breasts recouvrement.

Twenty prospective energetic components of UR and 24 prospective active components of EC were respectively collected, and 92 anti-hypertensive potential goals of UR-EC were obtained. According to FunRich enrichment results, the suitable indication of UR-EC ended up being pregnancy hypertension, which involved calcium signaling path, HIF-1 signaling path, neuroactive ligand receptor discussion, renin vascular tightening, VEGF signaling pathway, etc. In addition, AKT1, NOS2, ADRB2, F2, NOS3, SCN5 A, HTR2 A and JAK2 were considered as the key goals within the system. The molecular docking results indicated that the screened potential energetic components had high binding activity utilizing the key goals. This research preliminarily revealed that UR-EC could have healing impacts on maternity high blood pressure with regards to sedation, anti-hypertension, anti-inflammatory, anti-oxidation, improvement of vascular endothelial purpose and so on.Hypertension is a kind of persistent cardio system infection caused by a series of factors and carriers disorder, which is one of the group of Tibetan medication "Chalong disease", and it has a top price of disability and death. Zuomua Decoction is a classical Tibetan medicine for Chalong condition, but its apparatus is certainly not obvious. Therefore, in this paper we explored the multi-components, multi-targets and multi-channels device of Zuomua Decoction within the treatment of hypertension considering network pharmacology and molecular docking technology. First, the chemical components of Zuomua Decoction had been acquired when you look at the retrieval of standard Chinese medication systems pharmacology database(TCMSP), Asia National Knowledge Infrastructure(CNKI) and Wanfang database. The possibility targets of Zuomua Decoction had been predicted by BATMAN-TCM database, as well as the targets of hypertension had been gotten by utilizing DisGeNET database. The intersection of those two targets set was taken up to receive the potentiein conversation community, and in the comprehensive analysis, it absolutely was unearthed that Zuomua Decoction could lower blood circulation pressure by controlling renin angiotension aldosterone system, managing the focus of intracellular calcium and salt ions and regulating vasoconstriction and leisure. ACE, AGTR1, and ADRB2 were utilized while the carriers for molecular docking research on the the different parts of Zuoma Decoction, as well as the outcomes showed that the chemical aspects of Zuomua Decoction had a beneficial binding task with crucial objectives. The goal of this study is to supply a few ideas when it comes to detailed research of Zuoma Decoction within the treatment of high blood pressure, and offer systematic foundation for its medical logical application.This paper aimed to research the energetic elements and process of Taohong Siwu Decoction within the remedy for primary dysmenorrhea(PD) predicated on community pharmacology and molecular docking technology. Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP) was utilized to find the substance compositions and objectives of six herbs in Taohong Siwu Decoction. The goals for PD therapy were chosen through the databases of DrugBank, OMIM, TTD and CTD, and gene annotation of the objectives ended up being performed with UniProt database. Cytoscape 3.7.2 had been then utilized to create the drug-compound-target community. The protein-protein interaction(PPI) network ended up being built according to STRING, while the core targets of Taohong Siwu Decoction in the treatment of PD were selected according to the topological parameters. David database had been used for GO enrichment evaluation and KOBAS 3.0 was useful for KEGG enrichment evaluation. The molecular docking technology was utilized for connecting the components with higher medium values when you look at the network medical news with core objectives. The outcomes revealed that the system contained 36 compounds such quercetin, kaempferol, luteolin, myricanone and ferulic acid, and 99 targets such as for instance PTGS2, PTGS2, PGR and PPARG. Totally 102 GO terms were acquired by GO practical enrichment analysis(P<0.01), and 228 signal paths had been gotten by KEGG path enrichment(P<0.05), mainly concerning inflammatory facets, hormones legislation, central analgesia, amino acid kcalorie burning and spasmolysis. The results of molecular docking indicated that the key energetic elements can spontaneously bind into the objectives Puromycin . This study preliminarily disclosed the apparatus of Taohong Siwu Decoction for remedy for primary dysmenorrheal through multi-components, multi-targets and multi-pathways, supplying theoretical references for additional researches on method of Taohong Siwu Decoction.To explore the method of Sijunzi Decoction in the treatment of ulcerative colitis(UC) according to system pharmacology. The energetic components and corresponding targets of Sijunzi Decoction were Hepatitis management extracted with Traditional Chinese Medicine Systems Pharmacology Database and review Platform(TCMSP), and the goals had been standardised by using Uniprot database. The related objectives of UC had been acquired through GeneCards database and Disgenet database, and also the intersection objectives of medicines and conditions had been screened by R language. The visual regulation network of "active ingredient-disease target" of Sijunzi Decoction had been built by Cytoscape computer software, in addition to protein-protein interacting with each other network ended up being constructed by STRING database. The useful enrichment analysis of gene ontology(GO) and also the enrichment analysis of Kyoto encyclopedia of genes and genomes(KEGG) path were carried out on Bioconductor system, and some for the objectives had been validated by animal experiments. Through database analysi the appearance of IL-6 and caspase-3, and getting associated with apoptosis, irritation along with other pathways.This article analyze acupoint choice and traits of plaster therapy for stable persistent obstructive pulmonary di-sease(COPD) by information mining. The CNKI, VIP, CBM, WanFang, PubMed, EMbase, Cochrane Library had been retrieved for collecting clinical scientific studies of plaster treatment for stable COPD. After literature assessment, a complete of 46 organized reviews had been included. Frequency statistics, group evaluation, and Apriori correlation analysis were used to evaluate the design and characteristics of plaster treatment for stable COPD. The end result showed that the key acupoints for steady COPD were BL13, Dingchuan, CV22, BL23 and BL20. The acupoints used are primarily concentrated on the chest and back.

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