Increasing the Al mole fraction to 0.44, we observe an enhancement of misfit relaxation resulting in dislocation densities above 10(10) cm(-2). In the case of growth on AlGaN, strain relaxation is systematically stronger, with the corresponding increase in the dislocation density. In addition to the average relaxation trend of Ricolinostat the SL, in situ measurements indicate a periodic fluctuation of the in-plane lattice parameter, which is explained by the different elastic response of the GaN and AlGaN surfaces to the Ga excess at the growth front. The results are compared with GaN/AlN SLs designed

for near-infrared intersubband absorption. (C) 2011 American Institute of Physics. [doi:10.1063/1.3618680]“
“Sustained dexa methasone administration to horses results in insulin resistance, which may predispose them to laminitis. A single dose of dexamethasone is commonly used as a diagnostic aid, yet the effect of a single dose of dexa methasone on glucose homeostasis in horses is not well defined. The objective of this study was to characterize the change in glucose dynamics over time in response to a single dose of dexa methasone. A combined glucose-insulin tolerance test (CGIT) was performed on 6 adult geldings before and at 2, 24, and 72 h postdexa methasone (40 mu g/kg of BW, i.v.); a minimum of 1 wk of rest was allowed between treatments.

Before any treatment, the CGIT resulted in a hyperglycemic phase followed by a hypoglycemic phase. Dexa methasone affected glucose dynamics in 3 ways: 1) at 2 h, dexa methasone shortened the ascending branch AZD1390 datasheet of the negative phase ( P < 0.001) of the test, indicating moderate

insulin resistance; 2) at 24 h, dexa methasone impaired glucose clearance by extending the positive phase and eliminating the negative LEE011 order phase while insulin was elevated before the CGIT, indicating a decreased response to insulin; and 3) at 72 h, dexa methasone caused a deeper nadir value (P < 0.001) compared with predexa methasone, indicating an increased response to insulin. It was concluded that dexa methasone decreased the response to insulin as early as 2 h and maximally at 24 h. At 72 h, dexa methasone caused an increased response to insulin, which was unexpected.”
“Purpose: To determine the maternofetal pharmacokinetics of gadoterate meglumine in mice during the first 48 hours following maternal intravenous injection of a high dose of 0.5 mmol of gadolinium per kilogram.

Materials and Methods: All the studies complied with French law and the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. Balb/C mice (n = 23) at 16 days of gestation were examined for 48 hours after maternal intravenous administration of 0.5 mmol gadolinium per kilogram of gadoterate meglumine.