e., mistake discovered after patient received medication; patient discovery).
Main outcome measure: QREs for prescriptions.
Results: During a 45-month period, the remote telepharmacy group reported 47,078 prescriptions and 631 QREs compared with 123,346 prescriptions and 1,002
QREs in the standard pharmacy group. Results for near misses (pharmacy discovery) and errors (patient discovery) for the remote and comparison sites were 553 and 887 and 78 and 125, respectively. Percentage of “”where the mistake was caught”" www.selleckchem.com/products/btsa1.html (i.e., pharmacist check) for the remote and comparison sites were 58% and 69%, respectively.
Conclusion: This study reported a lower overall rate (1.0%) and a slight difference in medication dispensing error rates between remote telepharmacy sites (1.3%) and comparison sites (0.8%). Both rates are comparable Sotrastaurin with nationally reported levels
(1.7% error rate for 50 pharmacies).”
“Background: Few reports regarding the definition, epidemiology, and pathophysiology of acute decompensated heart failure (ADHF) are available. The clinical characteristics of 194 consecutive ADHF patients with abrupt onset of symptoms were investigated.
Methods and Results: Patients with acute coronary syndromes including acute myocardial infarction., acute pneumonia, severe valvular disease, and end-stage renal disease that required dialysis therapy were excluded. Patients were divided into 2 groups: rapid-progression group, onset within 24 hours before admission (n = 78), and gradual-progression group, onset more than 24 hours before admission (n 52). No significant differences were observed in the age, gender, prescriptions, and hematological data between the 2 groups. The proportion of patients who drank excessive water was higher in the rapid-progression group. Systolic blood pressure, diastolic blood pressure, heart rate, left ventricular ejection fraction, and left ventricular wall thickness were greater in patients in the rapid-progression group. Indexes indicating left ventricular diastolic function were significantly deteriorated in the rapid-progression
group.
Conclusion: Excessive water intake, acute hypertension, and SHP099 nmr diastolic dysfunction are associated with the pathophysiology of abrupt-onset ADHF Hypertensive patients with diastolic dysfunction should be treated cautiously to prevent the occurrence of ADHF. (J Cardiac Fail 2009:15:300-304)”
“Three new compounds, vibranether (1), myrrhlalkyldiol (2), vibralactone H (3), together with three known compounds, 2-methyl-6-p-tolylheptane-2,3-diol (4), 2-hydroxy-2-methyl-6-p-tolylheptan-3-one (5), and vibralactone (6), were isolated from the cultures of the basidiomycete Boreostereum vibrans. Their structures were determined on the basis of spectroscopic evidences (1D and 2D NMR, HRMS, UV, and IR data), chemical methods, and the literature data. The new compounds displayed no significant cytotoxicities against five human cancer cell lines (IC50>40M).