Results: There were 2.35 times (95% confidence interval [CI] 1.37-4.02) as many hospitalisations amongst infants from smoking compared with those from non-smoking families. Among non-prophylaxed infants, there were 2.53 Crenigacestat in vitro times (95% CI 1.27-4.94) as many
RSV hospitalisations from smoking than from non-smoking families and that excess hospitalisation was reduced to 1.03 times (95% CI 0.38-2.99) amongst prophylaxed infants. Familial smoking correlates significantly (p < 0.01) with other RSV risk factors: positive correlation with number of school-age siblings, history of family atopy, family wheeze and gestational age; negative correlation with birth weight and breast feeding.
Conclusions: Late-preterm infants from smoking families appear to be at heightened risk for severe RSV infection requiring hospitalisation of which the risk may be reduced with RSV prophylaxis.”
“In an attempt to identify new antimicrobial compounds with potential to be used as RG-7388 in vitro a bactericidal/fungicidal agent, a biomonitored study of extracts of Alternanthera brasiliana, which is used in Brazilian folk medicine as bactericidal, analgesic and anti-inflammatory,
was developed. Different techniques of evaluation have been used in the partitioned extracts of the antimicrobial activity associated with chromatographic methodologies. The work led to the isolation of two substances in the ethyl acetate extract, identified as quercetin and sitosterol glycoside and the antibacterial evaluation of these substances demonstrated that the flavonoid presented antibacterial action against S. aureus. Further studies
intend to identify new substances with antibacterial activity in extracts of A. brasiliana.”
“Objective: The aim of this study was to determine whether a failure of neonatal hearing screening affected the anxiety level of parents of high-risk infants.
Methods: Two hundred and eighty-eight parents of infants included in the neonatal MK-8931 hearing screening protocol of our Institution were tested with the Spielberger State-Trait Anxiety Inventory and with an open-question questionnaire investigating parents’ attitude to hearing problems in their child, done at the time of audiological follow-up. 105 were parents of high-risk infants who had been discharged from neonatal intensive care unit (NICU) and 183 of low-risk infants discharged from well-baby nursery.
Results: No differences in anxiety levels were seen between parents of high-risk infants passing and failing neonatal hearing screening using homogeneous case-control pairs. Additionally, no differences in the level of anxiety were found between parents of high-and low-risk infants failing neonatal auditory screening.
Conclusions: Failure of neonatal auditory screening does not affect the anxiety levels of parents of high-risk infants at post discharge from NICU. This finding is a key factor to be considered when evaluating the costs and benefits of tests for universal neonatal hearing screening.