Seroprevalence of leptospirosis was lowest for dogs > 10 years

Seroprevalence of leptospirosis was lowest for dogs > 10 years of age but was similar across other age strata.

Conclusions and Clinical Relevance-Leptospirosis can affect dogs of small and large

breeds and various ages. Although an increase HSP inhibitor review in proportions of positive MAT results was evident in the fall, monthly and annual variations suggested potential exposure in all months. Because of the limitations of MAT results and the limited number of serovars used in the test, bacterial culture should be used to identify infective Leptospira serovars. (J Am Vet Med Assoc 2010;237:293-298)”
“Case Description-A 15-kg (33-lb) pregnant female mixed-breed dog of unknown age was referred because of a 10-day history of difficulty breathing.

Clinical

Findings-Physical examination findings were dyspnea, tachypnea, decreased bronchovesicular sounds (bilateral), muffled heart sounds, and abdominal distention with palpable fetuses. Hematologic abnormalities selleck products included anemia, leukocytosis, and thrombocytosis. Abnormalities detected during serum biochemical analysis included decreases in concentrations of albumin, sodium, triglycerides, and total calcium and increases in activities of alkaline phosphatase, alanine aminotransferase, gamma-glutamyltransferase, aspartate aminotransferase, lactate dehydrogenase, and creatine kinase. Thoracic radiography revealed a diaphragmatic hernia with fetuses and a soft tissue or fluid opacity within the thoracic cavity.

Treatment Apoptosis inhibitor and Outcome-Exploratory celiotomy, ovariohysterectomy, partial sternotomy, placement of a right-sided

thoracostomy tube, and herniorrhaphy were performed. After surgery, pneumothorax developed, and the thoracostomy tube was used to remove pleural effusion and free air. The pneumothorax did not resolve after continuous drainage of the thoracic cavity for 4 days. Autologous blood pleurodesis was performed by infusion of 80 mL (6 mL/kg [2.73 mL/lb]) of whole blood. The pneumothorax resolved immediately after injection of the blood.

Conclusions and Clinical Relevance-Blood pleurodesis was used for resolution of pneumothorax in a dog after correction of a diaphragmatic hernia. Blood pleurodesis may provide a simple, safe, and inexpensive medical treatment for resolution of persistent (duration > 5 days) pneumothorax when surgery is not an option. (J Am Vet Med Assoc 2010;237:299-303)”
“Objective: To determine the impact of telephone medication therapy management (MTM) on medication- and health-related problems (MHRPs), medication adherence, and total drug costs for Medicare Part D participants.

Design: Quasiexperimental.

Setting: Regional Medicare Part D plan in Texas in 2007.

Participants: Medicare Part D beneficiaries who were MTM eligible.

Intervention: Pharmacist-provided telephone MTM consultation.

Main outcome measures: Change in MHRPs, medication adherence, and total drug costs from baseline to 12-month follow-up.

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