05). With the parameters measured in this study, we can locate the pituitary stalk by anterior commissure; thus, it is relatively safe to do the craniopharyngioma surgery through frontobasal interhemispheric approach when the pituitary stalk cannot be seen clearly because of the shelter of tumor, which will reduce both the unnecessary damage to the pituitary stalk and the probability of postoperative complications.”
“We aimed to investigate the effects of pretreatment with a small dose of dexmedetomidine on the cough caused by sufentanil during anesthetic induction.
Two hundred and forty patients undergoing
elective gynecological surgery under general EX 527 solubility dmso anesthesia were randomly allocated to 4 groups (n = 60, each group). Dexmedetomidine 0, 0.1, 0.25, and 0.5 mu g/kg was administered in 5 min to groups I, II, III, and IV, respectively, followed by the induction of general anesthesia with intravenous propofol, at a target concentration of 5 mu g/ml, and sufentanil 0.5 mu g/kg. The incidences and severity of cough that occurred within 1 min
after the injection of sufentanil were recorded, and the incidences of cardiovascular adverse events that occurred between the administration of the dexmedetomidine infusion and 1 min after tracheal intubation were recorded.
The incidences of cough in group II, group III, and group IV were lower than that in group I (6.7, 5.0, and 6.7 vs. 26.7 %, P < 0.01), while there were no significant differences between group GANT61 purchase II, group III, and group IV. The incidences of severe sinus bradycardia in group III and group IV were higher than that in group JIB 04 I (18.3 and 23.3 vs. 0.0 %, P < 0.01), while there was no significant difference between group I and group II. There was no significant difference in the incidence of low blood pressure among the four groups.
Dexmedetomidine at 0.10, 0.25, and 0.50 mu g/kg significantly reduced the incidence of sufentanil-induced cough during anesthetic induction, with the effect being most marked for
0.10 mu g/kg dexmedetomidine.”
“Objective: To determine the clinical and polysomnography outcomes in infants with laryngomalacia undergoing supraglottoplasty.
Methods: Infants (<1 year old) who underwent polysomnography pre- and post-supraglottoplasty at our tertiary referral center between 2003 and 2009 were reviewed retrospectively. Outcome measures included changes in stridor, sleep disordered breathing, swallowing, and polysomnography parameters before and after surgery. Pre- and postoperative distributions were compared using a Wilcoxon signed-rank test.
Results: 20 children met inclusion criteria. Statistically significant improvements were found in pre- to postoperative median values for apnea-hypopnea index (AHI) (median change: -6.4 points, p = 0.02) and obstructive apnea index (median change: -2.9 points, p = 0.01) values. Obstructive AHI, O(2) saturation nadir, and percentage of sleep spent with <90% O(2) saturation improved, although not significantly.