Bladder calculi were associated with lower 24-hour urinary pH (median 5.9 vs 6.4, p = 0.02), lower 24-hour urinary magnesium (median 106 vs 167 mmol, p = 0.01) and increased 24-hour urinary uric acid supersaturation (median 2.2 vs 0.6, p <0.01).

Conclusions: In this comparative prospective analysis patients with bladder outlet obstruction and benign prostatic https://www.selleckchem.com/products/yap-tead-inhibitor-1-peptide-17.html hyperplasia with bladder calculi were more likely to have a renal stone disease history, low urinary pH, low urinary magnesium and increased urinary uric acid supersaturation. These findings suggest that, like the pathogenesis of nephrolithiasis, the pathogenesis of bladder calculi is likely

complex with multiple contributing lithogenic factors, including metabolic

abnormalities and not just urinary stasis.”
“We investigated the association of single nucleotide polymorphisms of solute carrier family 6 member 11 (SLC6A11) (rs2304725, rs2272400, and rs2245532), SLC6A12 (rs216250 and rs557881) and SLC6A13 (rs2289954) with schizophrenia and its clinical selleck screening library symptoms. We found that rs216250 of SLC6A12 was correlated with the Scale for the Assessment of Negative Symptoms (SANS) scores. (C) 2011 Elsevier Ireland Ltd. All rights reserved.”
“Purpose: We evaluated trends and associated characteristics in the use of robotics for pyeloplasty as treatment for ureteropelvic junction obstruction.

Materials and Methods: Data from the Nationwide Inpatient Sample were used to evaluate pyeloplasty trends from 2005

to 2010. Patients treated with pyeloplasty and procedure method (robotic, laparoscopic or open) were identified by ICD-9-CM codes. Coding for robotics was initiated in the fourth quarter of 2008. Multivariable analysis was performed to examine characteristics affecting the odds of undergoing robotic pyeloplasty from vs other approaches to pyeloplasty.

Results: Weidentified 3,947 pyeloplasties performed between 2005 and 2010, including 1,642 since the fourth quarter of 2008. There was a statistically significant increase in the number of robotic pyeloplasties (p <0.001). Mean total charges for robotic vs nonro-botic procedures were $40,200 vs $37,817 (p = 0.106). Characteristics related to undergoing a robotic procedure included surgery at a teaching hospital (OR 1.29, 95% CI 1.04-1.59, p = 0.021) and in the Northeast (OR 1.54, 95% CI 1.17-2.04, p = 0.002) or Midwest (OR 1.62, 95% CI 1.23-2.12, p <0.001) compared with the South. When the primary payer was Medicaid vs private insurance, patients were 46% less likely to undergo the procedure robotically (p <0.001). There was no significant difference in charges between robotic and open pyeloplasty.

Conclusions: The number of robotic pyeloplasties performed quarterly in the United States is increasing, although there are disparities in the adoption of the robotic approach among geographic regions and hospital types.