(C) 2011 American Institute of Physics. [doi: 10.1063/1.3656687]“
“Many different surgical procedures have been employed in the treatment of fracture dislocation at the middle to lower cervical spine. However, consistent protocols and procedures have not been fully established for the surgical correction of an irreducible old cervical fracture dislocation associated with spinal deformity.
We report a case of irreducible cervical fracture dislocation and kyphoscoliosis, in which surgical
simulation using a three-dimensional full-scale model was useful for circumferential corrective osteotomy at the C6-C7 level. 3 Methyladenine A 56-year-old man was diagnosed with an irreducible fracture dislocation at the C6-C7 level
2 months after a motor vehicle accident. He showed torticollis, and complained of severe pain in his neck and left upper arm. Radiographic examinations revealed that the C6 vertebra was translated anteriorly and laterally to the C7 vertebra. A bony union had progressed at the fracture site, showing rigid cervico-thoracic kyphoscoliosis. To assist in the preoperative planning, we created a three-dimensional, full-scale model from the patient’s computed tomography data. Using the model, we performed a simulation of the planned circumferential corrective osteotomy at the C6-C7 level.
Through the simulation, we could evaluate the deformed bony structures around the vertebral arteries at the C6-C7 level accurately. At the time of the actual surgery, corrective osteotomy combined with spinal fusion (C5-T2) with STA-9090 cell line a pedicle screw-rod system was accomplished successfully without any neurovascular complications. After surgery, the patient experienced
relief from pain, and his neck posture became normal.
Surgical simulation using a three-dimensional, full-scale model was useful for improving the accuracy and safety of circumferential corrective osteotomy Liproxstatin-1 of the cervical spine.”
“Unilateral and bilateral hand transplantations have been performed worldwide with good mid-term functional results. An above-elbow bilateral transplantation was performed in a 29-year-old male patient from a fully HLA-mismatched donor. Alemtuzumab induction and steroid-free maintenance immunosuppression with tacrolimus and mycophenolate was used. Due to acute rejection, steroids were introduced at 6 months. Three acute rejection episodes occurred, one treated with alemtuzumab. New-onset diabetes after transplant, dyslipemia and worsening of previous high blood pressure required treatment. At 26 months post-transplantation, the patient has excellent elbow active movement, active flexion and extension of the thumb and fingers, useful sensation and a gainful job. Based on the functional results of the case reported, bilateral trans-humeral transplantation could be a viable treatment for selected bilateral above-elbow amputees.