In order to improve the knowledge on its metabolite profile and biological properties, three different polar extracts (decoction, ethanol and hydrolate) of S. parvifolia collected in three different places of Jujuy Province (Argentina) were studied. The screening by DPPH center dot scavenging assay allowed selecting the sample to be used in further analyses. Fourteen phenolic

compounds were determined by HPLC-DAD. The decoction presented the highest phenolic content, rosmarinic acid and the pair epigallocatechin-3-O-gallate plus epicatechin-3-O-gallate being the main metabolites. Twenty-eight volatile compounds were determined by GC-IT/MS, piperitenone, Selleckchem FG4592 piperitenone oxide and pulegone being the compounds present in higher amounts. A concentration-dependent effect

was noticed against nitric oxide and superoxide radicals. Decoction proved to be the most active extract against all radicals, representing a good, cheap and feasible source to recover natural antioxidants for food industry. Good acetylcholinesterase and butyrylcholinesterase inhibitory capacities were also found for all extracts. As far as we know, this is the first study assessing these biological activities. (C) 2013 Elsevier B.V. All rights reserved.”
“A case of seminoma found in an adult guinea fowl (Numida meleagris) that has been exhibited in a zoo is reported. The right testis was extremely enlarged and NCT-501 manufacturer replaced by round and polyhedral pleomorphic neoplastic cells showing nest, sheet, and diffuse growth patterns. The neoplastic RepSox order cells had acidophilic cytoplasm and hyperchromatic and eccentrically placed nuclei. Metastatic lesions composed of diffuse growth of neoplastic cells similar to those of the primary tumor were seen in the liver, lungs, kidneys, and heart, and neoplastic emboli were often detected within blood vessels of these

organs, indicating hematogenous metastasis. This is the first report of malignant seminoma with multiple metastases in the visceral organs in the guinea fowl.”
“Background/Aims: Previous studies point to an association between childhood sexual abuse (CSA) and auditory hallucinations (AH). However, methodological issues limit the strength of these results. Here we compared childhood abuse between psychotic disorder patients and healthy control subjects using a reliable measure of abuse, and assessed the relationship between CSA and AR.\n\nMethods: 114 psychotic disorder patients and 81 healthy control subjects were administered the Structured Clinical Interview of the DSM-IV (SCID) and the Childhood Trauma Questionnaire (CTQ). We compared the severity of abuse between groups, and tested the relationship between different types of childhood abuse and specific psychotic symptoms.\n\nResults: Psychotic patients reported more childhood abuse than controls (p < .001).