Methods: In a retrospective case-control study, we compared labor course, total labor duration, and obstetric complications in 127 women who received cervical cerclage with 254 controls. Results: There was no significant difference in the duration of the first stage of labor (477 +/- 576 vs. 373 +/- 437 min, p = 0.075) or the second stage of labor (18 +/- 17 vs. 20 +/- 19 min, p = 0.287) between the 2 groups. In the multivariate

analysis, women in the cerclage group were found to be significantly more likely to have a prolonged latent phase (odds ratio [OR], 2.802; 95% confidence interval [CI], 1.103-7.120; p = 0.030), cervical laceration (OR, 15.984; 95% CI, 3.169-80.624; p = 0.001), and treatment with tocolytics (OR, 2.580; 95% CI, 1.217-5.468; p = 0.013) than the control group. No significant difference was noted in cesarean delivery rate. Conclusions:

Etomoxir clinical trial Cervical cerclage is more likely to be associated with a prolonged latent phase and minor selleck obstetric complications, but not with a difference in the total duration of labor or increased cesarean delivery rate.”
“A new triterpenoid, 3,4-seco-lupane-20(29)-ene-3,28-dioic acid (1), together with three known lignans, (-)-schisandrin B (2), (-)-sesamin (3) and (-)-syringaresinol (4), was isolated from the pulp of Acanthopanax senticosus (Rupr. et Maxim) Harms. Their structures were elucidated by means of physicochemical properties and spectroscopic methods (1D, 2D-NMR and MS).”
“Background Anastomotic ulcers (AUs) after Roux-en-Y gastric bypass (RYGB) occur in up to 16 % of patients. In an international survey among members of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO), current preventative and therapeutic strategies in AU were analyzed.

Methods An Internet-based survey was performed.

Results One hundred eighty-nine surgeons completed the survey. Preoperative screening BB-94 research buy for Helicobacter pylori is performed by 65 %. Eighty-eight

percent of them prophylactically prescribe antacids for 3 months after surgery (interquartile range (IQR) 1-6). In case of AU, 99 % of participants opt for proton pump inhibitors (PPIs) either alone (60 %) or in combination with sucralfate (39 %). After ulcer resolution, 52 % continue PPI for 6 (3-6) months. In case of AU recurrence, 56 % continue with conservative treatment. In contrast, 41 % of them favor a renewal of the gastrojejunal anastomosis either combined with truncal vagotomy (18 %) or with gastric remnant resection (13 %), and only 2 % choose to resect both gastric pouch and gastric remnant with subsequent reconstruction by esophagojejunostomy. In case of recurrence after surgical revision, 46 % of participants opt again for a conservative approach, while 36 % chose to redo the gastrojejunostomy once again.

Conclusions The majority of bariatric surgeons recommend preoperative screening and eradication of H. pylori as well as prophylactic use of PPI.