We have coupled GPF and the

gene finding Tariquidar in vitro program AUGUSTUS in a way that provides automatic structural annotations of the Chlamydomonas reinhardtii genome, using highly unbiased GPF evidence. A comparison of the AUGUSTUS gene set incorporating GPF evidence to the standard JGI FM4 (Filtered Models 4) gene set reveals 932 GPF peptides that are not contained in the Filtered Models 4 gene set. Furthermore, the GPF evidence improved the AUGUSTUS gene models by altering 65 gene models and adding three previously unidentified genes.”
“Niche theory and neutral theory are two major developments aiming at explaining patterns of biodiversity observed in nature. Both theories have been found relevant either separately or simultaneously in some real communities, and it has been theoretically demonstrated that they can produce similar species abundance distributions. However, it remains controversial whether the two theories can produce similar patterns via different mechanisms, or can interact to jointly produce the observed diversity patterns, or whether the patterns generated by the neutral model are robust to niche structure. Here we show that, although the neutral model proposed for spatially discrete communities remains robust to strong niche structure for high-diversity communities, the inclusion of more realistic niche differentiation modes greatly improves

the goodness of fit to Indo-Pacific coral reefs. Actually, the multiple discrete communities’ neutral model, due to its underestimation

check details of the number or abundance of common species, fails to capture the combination learn more of many rare species and a few highly abundant species that characterize the Indo-Pacific coral reef communities. By incorporating niche structure into the multiple discrete communities’ model, the hybrid niche-neutral models can successfully reproduce both the species-based and individual-based abundance distribution patterns observed in the coral reefs. We proposed that both niche theory and neutral theory may be involved in explaining the structure of such communities. Our results also suggest a negative relationship between per capita birth to death ratio and immigration among different guilds of coral species, which clearly deserves further investigation. (C) 2012 Elsevier Ltd. All rights reserved.”
“The components that enable cells and organisms to fulfill a plethora of chemical and physical reactions, including their ability to metabolize, replicate, repair and communicate with their environment are mostly based on the functioning of highly complex cellular machines which are to a large extent composed of proteins. With the development of MS techniques compatible with the analysis of minute amounts of biological material, it has become more and more feasible to dissect the composition and modification of these protein machineries.